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Brodys Human Pharmacology 5th Edition Crespo Wecker Dunaway Test Bank

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Brodys Human Pharmacology 5th Edition Crespo Wecker Dunaway Test Bank

ISBN-13: 978-0323053747

ISBN-10: 0323053742

 

Description

Brodys Human Pharmacology 5th Edition Crespo Wecker Dunaway Test Bank

ISBN-13: 978-0323053747

ISBN-10: 0323053742

 

 

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Below you will find some free nursing test bank questions from this test bank:

Wecker: Brody’s Human Pharmacology, 5th Edition

Chapter 48: Bacterial Folate Antagonists, Fluoroquinolones, and Other Antibacterial Agents

 

Test Bank

Multiple Choice

 

  1. The combination of trimethoprim and sulfamethoxazole (TMP-SMZ) is frequently used because:

 

  1. The TMP covers aerobic bacteria that the SMZ does not
  2. The combination has no potential side effects
  3. The SMZ potentiates the action of TMP
  4. The SMZ covers anaerobic bacteria that TMP does not
  5. The TMP covers fungi that SMZ does not

 

ANS: E. TMP and SMX are used effectively in combination to achieve synergistic effects, which they accomplish by blocking different steps in folic acid synthesis. Moreover, sulfamethoxazole potentiates the action of TMP by reducing the dihydrofolate competing with TMP for binding to dihydrofolate reductase.

 

  1. When the resistance of urinary tract Enterobacteriaceae to TMP-SMZ is higher than 20%, which of the following is the most commonly used drug class as alternative therapy?

 

  1. Macrolide
  2. Penicillin
  3. Vancomycin
  4. Fluoroquinolones
  5. Tetracycline

 

ANS: D. Ciprofloxacin, a flouroquinolone, is the best choice among the above after TMP-SMZ for the treatment of Enterobacteriaceae and uncomplicated urinary tract infections.