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Essentials of Pharmacology for Health Occupations 6th Edition Woodrow Smith Test Bank

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Essentials of Pharmacology for Health Occupations 6th Edition Woodrow Smith Test Bank

ISBN-13: 978-1435480339

ISBN-10: 1435480333

 

Description

Essentials of Pharmacology for Health Occupations 6th Edition Woodrow Smith Test Bank

ISBN-13: 978-1435480339

ISBN-10: 1435480333

 

 

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CHAPTER 22:  ANTICONVULSANTS, ANTIPARKINSONIAN DRUGS, AND AGENTS FOR ALZHEIMER’S DISEASE

 

MATCHING

 

Match each mechanism of action below with the appropriate medication or category.

 

a. Reduces the number and/or severity of seizures
b. Alters Dopamine release and has anticholinergic properties
c. Blocks the enzyme responsible for metabolizing levodopa
d. Used to treat Parkinson-like tremors associated with long-term use of the antipsychotics
e. Have a greater specificity for dopamine receptors

 

 

  1. Anticonvulsants

 

  1. Anticholinergics

 

  1. COMT

 

  1. Amantadine

 

  1. Dopamine agonist

 

  1. ANS:  A                    PTS:   1

 

  1. ANS:  D                    PTS:   1

 

  1. ANS:  C                    PTS:   1

 

  1. ANS:  B                    PTS:   1

 

  1. ANS:  E                    PTS:   1

 

Match each term below with the appropriate description.

 

a. Characterized by a 10-30 second loss of consciousness without falling, usually noted in children
b. True neurologic emergency
c. Characterized by loss of consciousness, falling, and generalized tonic followed by clonic contractions
d. Complex symptoms such as confusion, impaired understanding and judgment, staggering, purposeless movements, bizarre behavior, and unintelligible sounds
e. Seizures affecting only one side of the body

 

 

  1. Unilateral seizures

 

  1. Tonic-clonic seizures

 

  1. Partial seizures

 

  1. Absence seizures

 

  1. Status epilepticus

 

  1. ANS:  E                    PTS:   1

 

  1. ANS:  C                    PTS:   1

 

  1. ANS:  D                    PTS:   1

 

  1. ANS:  A                    PTS:   1

 

  1. ANS:  B                    PTS:   1

 

MULTIPLE CHOICE

 

  1. Tonic-clonic seizures are characterized by:
a. loss of consciousness, falling, and generalized tonic, followed by clonic contractions of the muscles.
b. 10-30 second loss of consciousness with no falling.
c. confusion, impaired understanding and judgment, staggering, purposeless movements, bizarre behavior, and unintelligible sounds, but no convulsions.
d. affecting only one side of the body.

 

 

ANS:  A

 

  Feedback
A Correct!
B This is characteristic of absence epilepsy.
C These are characteristics of psychomotor epilepsy.
D This is characteristic of unilateral seizures.

 

 

PTS:   1

 

  1. Which of the following is TRUE of absence seizures?
a. Most commonly occurs in adults
b. Most commonly occurs in children
c. Involves less than 30 minutes between seizures
d. Involves an abrupt loss of consciousness followed by synchronous contractions of the muscles

 

 

ANS:  B

 

  Feedback
A This occurs in children.
B Correct!
C This refers to status epilepticus.
D This is characteristic of tonic-clonic seizures.

 

 

PTS:   1

 

  1. Partial seizures may include which of the following characteristics?
a. Loss of consciousness, falling, and generalized tonic, followed by clonic contractions of the muscles
b. 10-30 second loss of consciousness with no falling
c. Preceded by an aura
d. Affected on only one side of the body

 

 

ANS:  C

 

  Feedback
A These are characteristics of tonic-clonic seizures.
B This is characteristic of absence seizures.
C Correct!
D This is characteristic of unilateral seizures.

 

 

PTS:   1

 

  1. Which statement is TRUE of unilateral seizures?
a. Involves loss of consciousness and generalized tonic contractions of the muscles
b. 10-30 second loss of consciousness
c. Staggering, purposeless movements, bizarre behavior, and unintelligible sounds
d. Affects only one side of the body

 

 

ANS:  D

 

  Feedback
A These are characteristics of tonic-clonic seizures.
B This is characteristic of absence seizures.
C These are characteristics of psychomotor seizures.
D Correct!

 

 

PTS:   1

 

  1. The drug used for management of absence epilepsy is:
a. ethosuximide (Zarontin) c. carbamazepine (Tegretol).
b. phenytoin (Dilantin). d. lamotrigine (Lamictal).

 

 

ANS:  A

 

  Feedback
A Correct!
B This is used for the prophylactic treatment of grand mal and psychomotor seizures.
C This medication may actually aggravate absence seizures.
D This is used for the management of psychomotor seizures.

 

 

PTS:   1

 

  1. Which medication is NOT used to manage psychomotor seizures?
a. Dilantin c. Tegretol
b. Celebrex d. Topamax

 

 

ANS:  B

This is a COX-2 inhibitor.

 

PTS:   1

 

  1. Which drug is used for the management of tonic-clonic or generalized seizures?
a. Zarontin c. Tegretol
b. Amantadine d. Aricept

 

 

ANS:  C

 

  Feedback
A Used only for absence seizures.
B Indicated for Parkinson’s disease.
C Correct!
D Indicated for Alzheimer’s disease.

 

 

PTS:   1

 

  1. Dilantin may be used to treat all of the following, EXCEPT:
a. absence seizures. c. partial seizures.
b. tonic-clonic seizures. d. status epilepticus.

 

 

ANS:  A                    PTS:   1

 

  1. Side effects of phenytoin (Dilantin)  include:
a. anorexia and aggression.
b. blurred vision, nystagmus, and diplopia.
c. hallucinations.
d. dyskinesias and behavioral changes.

 

 

ANS:  B

In addition to these, Dilantin may also cause sedation, ataxia, headache, gingivitis, GI symptoms, rash, dermatitis, Stevens-Johnson syndrome, lupus-like symptoms, megaloblastic anemia, and osteomalacia.

 

PTS:   1

 

  1. An advantage of using Tegretol over other medications to treat seizures is:
a. minimal sedation and cognitive adverse affects.
b. does not cause Stevens-Johnson syndrome.
c. no medication interactions.
d. better choice in cardiac and renal patients.

 

 

ANS:  A

 

  Feedback
A Correct!
B There is an increased incidence of Stevens-Johnson syndrome in Asians with HLAB1502 allele.
C There are multiple interactions with other medications and foods.
D It may cause cardiac, hematological, kidney, liver, and pancreatic complications.

 

 

PTS:   1

 

  1. Which of the following is NOT a side effect of Sinemet?
a. Dyskinesias, behavioral changes, and syncope
b. Psychosis and depression
c. Confusion, sleep disturbances, and hallucinations
d. Headache, hypertension, CHF, and edema

 

 

ANS:  D

Other side effects include anorexia, anxiety, agitation, and confusion.

 

PTS:   1

 

  1. Side effects of amantadine (Symmetrel) DO NOT  include:
a. hypertension. c. edema.
b. CHF. d. CNS disturbances.

 

 

ANS:  A

Other side effects include depression, confusion, hallucinations, anxiety, irritability, nervousness, dizziness, headache, weakness, insomnia, GI distress, constipation, and urinary retention.

 

PTS:   1

 

  1. Anticholinergic agents may have which of the following side effects?
a. Dyskinesias, psychosis, and syncope
b. Hallucinations, confusion, and hypotension
c. Nausea, vomiting, diarrhea, and anorexia
d. CHF, edema, and hypotension

 

 

ANS:  C                    PTS:   1

 

  1. Dopamine agonists are commonly used:
a. to delay onset of levodopa-caused motor complications in Parkinson’s disease.
b. for the treatment of tonic seizures.
c. in order to decrease the amount of Aricept used in Alzheimer’s patients.
d. to treat restless legs syndrome.

 

 

ANS:  A

 

  Feedback
A Correct!
B Dopamine agonists are not used to treat seizures.
C Use of dopamine agonists may reduce the amount of levodopa required in advanced Parkinson’s disease.
D Dopamine agonists are not used to treat restless legs syndome.

 

 

PTS:   1

 

  1. Which of the following responses indicates a need for further education regarding anticonvulsant medications?
a. “I will be extra careful with my oral hygiene”
b. “I will get and wear a MedicAlert tag or bracelet at all times”
c. “I will take the medication with grapefruit juice to lessen side effects”
d. “I will report side effects to my doctor”

 

 

ANS:  C

 

  Feedback
A This is a correct understanding of instructions.
B This is a correct understanding of instructions.
C Correct!
D This is a correct understanding of instructions.

 

 

PTS:   1

 

  1. Which of the following responses indicates a need for further education regarding antiparkinsonian drugs?
a. “I will avoid abruptly stopping my medication.”
b. “I should see effects of the medication within the next couple of days.”
c. “I will use caution with driving or operation of machinery.”
d. “I will report any signs that the drug is no longer effective.”

 

 

ANS:  B

 

  Feedback
A This is a correct understanding of instructions.
B Correct!
C This is a correct understanding of instructions.
D This is a correct understanding of instructions.

 

 

PTS:   1

 

  1. Possible causes of epilepsy include:
a. intracranial infection. c. hypoglycemia.
b. intoxication. d. all of the above.

 

 

ANS:  D                    PTS:   1

 

  1. Alzheimer’s disease may be treated with which of the following?
a. Exelon c. Requip
b. Mirapex d. All of the above

 

 

ANS:  A                    PTS:   1

 

  1. RLS may be treated with which of the following?
a. Neurontin c. Opioids
b. Benzodiazepines d. All of the above

 

 

ANS:  D                    PTS:   1

 

  1. Which of the following drugs may aggravate RLS?
a. Antihistamines c. Oxycodone
b. Neurontin d. All of the above

 

 

ANS:  A                    PTS:   1

 

TRUE/FALSE

 

  1. Tonic-clonic seizures were formally known as grand mal seizures.

 

ANS:  T                    PTS:   1

 

  1. Febrile seizures are a predictor of future seizures in adulthood.

 

ANS:  F                    PTS:   1

 

  1. Childhood febrile seizures may signify an underlying infection.

 

ANS:  T                    PTS:   1

 

  1. “Clonic” refers to extension of the trunk and extremities during seizure activity.

 

ANS:  F

This describes tonic activity.

 

PTS:   1

 

  1. Absence seizures are classified as nonconvulsive.

 

ANS:  T                    PTS:   1

 

  1. Temporal lobe seizures describe myoclonic seizures.

 

ANS:  F

Temporal lobe seizures are also known as partial or psychomotor seizures.

 

PTS:   1

 

  1. Most children who experience febrile seizures require anticonvulsant therapy.

 

ANS:  F

Identifying the cause of the fever and using antipyretics to control the fever are the necessary treatments.  Anticonvulsant therapy is not recommended for simple febrile seizures.

 

PTS:   1

 

  1. RLS or restless legs syndrome is a sensorimotor neurologic disorder characterized by a distressing urge to move the legs.

 

ANS:  T

Definition taken directly from the text.

 

PTS:   1

 

  1. All cholinesterase inhibitors used to treat Alzheimer’s disease may cause GI upset.

 

ANS:  T                    PTS:   1

 

  1. An FDA alert sent to health care professionals advised of an increased risk of suicidal ideation and behavior in patients receiving anticonvulsants.

 

ANS:  T                    PTS:   1

 

  1. The dosages of Mirapex and Requip are the same dosage when given for RLS as is used for Parkinson’s disease.

 

ANS:  F

The dosages are reduced for RLS to 10-20% of that used for Parkinson’s disease.

 

PTS:   1