Description
Roachs Introductory Clinical Pharmacology 9th Edition Ford Roach Test Bank
ISBN-13: 978-1469825052
ISBN-10: 1469825058
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Chapter 26- Cholinergic Drugs
| 1. | Which of the following are true about the enzyme acetylcholinesterase? Select all that apply: | |
| A) | Acetylcholinesterase makes the parasympathetic nervous system function differently. | |
| B) | Acetylcholinesterase inactivates the neurotransmitter serotonin. | |
| C) | Acetylcholinesterase activates the neurotransmitter acetylcholine. | |
| D) | Acetylcholinesterase inactivates the neurotransmitter norepinephrine. | |
| E) | Acetylcholinesterase activity results in the prevention of nerve synapses to continue nerve impulses. | |
| 2. | Which of the following medical conditions can be treated with cholinergic drugs? Select all that apply: | |
| A) | Urinary retention | |
| B) | Overactive bladder | |
| C) | Myasthenia gravis | |
| D) | Parkinson’s disease | |
| E) | Graves’ disease | |
| 3. | The nurse should alert a client to which of the following adverse effects of pilocarpine (Pilopine) ophthalmic drops? Select all that apply: | |
| A) | Nausea | |
| B) | Headache | |
| C) | Nasal congestion | |
| D) | Decreased visual acuity | |
| E) | Decreased auditory acuity | |
| 4. | A nurse should alert a client to which of the following adverse effects of pyridostigmine (Mestinon)? Select all that apply: | |
| A) | Constipation | |
| B) | Nausea | |
| C) | Dry mouth | |
| D) | Skin flushing | |
| E) | Muscle rigidity | |
| 5. | A physician orders guanidine 15 mg/kg/day mouth in fourdivided doses for a client with Eaton-Lambert disease. If the client weighs 147 lbs, how many milligrams will the nurse need to administer to the client daily? |
| 6. | If a client is to receive 1000 mg/day of guanidine per day in four divided doses, how many tablets should the nurse administer to the client at each dose if the tablets are 125 mg each? |
| 7. | A nurse should review a client’s medical conditions prior to administering a cholinergic drug as their use is contraindicated in clients with which of the following medical conditions? Select all that apply: | |
| A) | Pancreatitis | |
| B) | Diabetes | |
| C) | Asthma | |
| D) | Hyperthyroidism | |
| E) | Peptic ulcer disease | |
| 8. | The nurse should be cautious and closely monitor clients receiving ambenonium (Mytelase) with which of the following medical conditions? Select all that apply: | |
| A) | Diabetes | |
| B) | Hypertension | |
| C) | Tachycardia | |
| D) | Epilepsy | |
| E) | Megacolon | |
| 9. | Which of the following medication when administered with a cholinergic drug will result in increased neuromuscular blocking effects? Select all that apply: | |
| A) | Amoxicillin (Amoxil) | |
| B) | Tobramycin (Tobi) | |
| C) | Cephalexin (Keflex) | |
| D) | Neomycin (Neo-Rx) | |
| E) | Clarithromycin (Biaxin) | |
| 10. | Which of the following medication when administered with a cholinergic drug will result in increased adverse effects of the cholinergic drug? Select all that apply: | |
| A) | Prednisone | |
| B) | Oxycodone | |
| C) | Diclofenac | |
| D) | Dexamethasone | |
| E) | Ibuprofen | |
| 11. | Prior to administering bethanechol (Urecholine) to a client, the nurse’s preadministration assessment should include which of the following? Select all that apply: | |
| A) | Palpation of the bladder | |
| B) | Palpation of the thyroid | |
| C) | Blood glucose | |
| D) | Blood pressure | |
| E) | Pulse rate | |
| 12. | Prior to administering ambenonium (Mytelase) to a client, the nurse’s preadministration assessment should include which of the following? Select all that apply: | |
| A) | Palpation of the bladder | |
| B) | Palpation of the thyroid | |
| C) | Signs of muscle weakness | |
| D) | Signs of difficulty breathing | |
| E) | Drooping eyelids | |
| 13. | A nurse should notify the physician immediately if a client taking a cholinergic drug develops which of the following cholinergic crisis symptoms?? Select all that apply: | |
| A) | Hypoglycemia | |
| B) | Excessive salivation | |
| C) | Severe abdominal cramping | |
| D) | Muscle rigidity | |
| E) | Muscle spasms | |
| 14. | Which of the following cholinergic drugs are administered topically? Select all that apply: | |
| A) | Ambenonium (Mytelase) | |
| B) | Pilocarpine (Pilopine) | |
| C) | Carbachol (Miostat) | |
| D) | Pyridostigmine (Mestinon) | |
| E) | Edrophonium (Tensilon) | |
| 15. | Which of the following cholinergic drugs are administered orally? Select all that apply: | |
| A) | Ambenonium (Mytelase) | |
| B) | Pilocarpine (Pilopine) | |
| C) | Carbachol (Miostat) | |
| D) | Pyridostigmine (Mestinon) | |
| E) | Edrophonium (Tensilon) | |
| 16. | In order to promote optimal response to therapy the nurse should discuss which of the following with the client and his/her family? Select all that apply: | |
| A) | Purpose of drug therapy | |
| B) | Tolerance will develop to adverse reactions | |
| C) | How to monitor blood glucose | |
| D) | Adverse reactions that can occur with drug therapy | |
| E) | Which adverse reactions to report to the physician | |
| 17. | It is important for a nurse to understand which body systems are affected cholinergic drug adverse reactions, as this will determine how the nurse should assess the client. Which of the following body systems are affected cholinergic drug adverse reactions? Select all that apply: | |
| A) | Endocrine | |
| B) | Circulatory | |
| C) | Respiratory | |
| D) | Gastrointestinal | |
| E) | Central nervous | |
| 18. | The physician has asked the nurse to administer Edrophonium (Tensilon) to a client to aid in the diagnosis of Myasthenia gravis. The order is for the client to receive 3 mg of Edrophonium (Tensilon) intravenously. If it is available in a 10 mg/mL vial, how many milliliters will need to be administered to the client? |
| 19. | A client is to receive Pyridostigmine (Mestinon) 300 mg BID, if the drug is available in a 60 mg tablet, how many tablets will the nurse administer to the client with each dose? |
| 20. | A client is to receive ambenonium (Mytelase) 35 mg TID, if the drug is available in a 10 mg caplet, how many caplets will the nurse administer to the client with each dose? |
| 21. | A nurse is caring for a patient undergoing glaucoma treatment. The nurse knows that which of the following combinations of drugs need to be administered to the patient to produce an additive effect on the treatment? | |||
| A) | Carbachol and pilocarpine | C) | Pilocarpine and atropine | |
| B) | Atropine and carbachol | D) | Corticosteroids and atropine | |
| 22. | A patient has been prescribed edrophonium for myasthenia gravis. Which of the following can the nurse monitor as a general adverse reaction in the patient? | |||
| A) | Seizure disorder | C) | Abdominal discomfort | |
| B) | Reduction of visual acuity | D) | Cardiac arrhythmias | |
| 23. | A nurse is caring for a patient with urinary retention. The patient has been prescribed Urecholine. For which category of patients should the nurse take precautions when administrating Urecholine? | |
| A) | Patients with Raynaud’s disease | |
| B) | Patients with bradycardia | |
| C) | Patients with recent myocardial infarction | |
| D) | Patients with hyperthyroidism | |
| 24. | A patient with glaucoma has been prescribed carbachol. The patient informs the nurse that he recently had a bacterial infection and has been taking an aminoglycoside antibiotic. Why should the nurse caution the patient against the use of aminoglycoside antibiotics along with carbachol? | |
| A) | Increased carbachol levels result in toxicity | |
| B) | Increased risk of hypotension | |
| C) | Increased neuromuscular blocking effect | |
| D) | Decreased effect of the carbachol | |
| 25. | A nurse is caring for a patient with urinary retention. Which of the following conditions should the nurse notify the primary healthcare provider as part of the ongoing assessment? | |
| A) | Failure to void after drug administration | |
| B) | Frequent vomiting after drug administration | |
| C) | Increase in abdominal pain after drug administration | |
| D) | Occurrence of blood in urine after drug administration | |
| 26. | A nurse is caring for a patient with myasthenia gravis at a healthcare facility. The patient has been administered ambenonium. Which of the following symptoms of drug under dosage should the nurse monitor in the client? | |||
| A) | Clenching of the jaw | C) | Difficulty in breathing | |
| B) | Muscle spasms | D) | Abdominal cramping | |
| 27. | The nurse is developing a teaching plan for an outpatient receiving cholinergic drugs. What should be the role of the nurse when developing a teaching plan? | |
| A) | Suggest the patient avoid fiber rich food during therapy | |
| B) | Suggest the patient adapt a self blood pressure measurement habit | |
| C) | Review the purpose of the drug therapy with the patient and family | |
| D) | Review the patient’s previous history of disorders | |
| 28. | A nurse is caring for a patient with glaucoma. The patient has been prescribed a cholinergic drug. What should the nurse assess in the patient? | |
| A) | Check the eye daily for evidence of redness | |
| B) | Check for double vision in the patient | |
| C) | Check for blurred vision in the patient | |
| D) | Check for temporary visual impairment | |
| 29. | A nurse is assigned to care for a patient who has been prescribed an ophthalmic cholinergic drug. In which of the following cases is the use of ophthalmic cholinergic drug contraindicated? | |||
| A) | Patients with cataracts | C) | Patients with megacolon | |
| B) | Patients with diabetic retinopathy | D) | Patients with corneal abrasion | |
Answer Key
| 1. | A, E |
| 2. | A, C |
| 3. | B, D |
| 4. | B, D |
| 5. | 1000 mg/day |
| 6. | 2 tablets/dose |
| 7. | C, D, E |
| 8. | B, D |
| 9. | B, D |
| 10. | A, D |
| 11. | A, D, E |
| 12. | C, D, E |
| 13. | B, C, D, E |
| 14. | B, C |
| 15. | A, D |
| 16. | A, B, D, E |
| 17. | B, C, D, E |
| 18. | 0.3 mL |
| 19. | 5 tablets/dose |
| 20. | 3.5 caplets/dose |
| 21. | A |
| 22. | D |
| 23. | B |
| 24. | C |
| 25. | A |
| 26. | C |
| 27. | C |
| 28. | A |
| 29. | D |
